Florence Cathedral's dome at dusk
Milan · Venice · Florence · Rome · 14 days itinerary

Milan, Venice, Florence and Rome in 14 Days

Photo: Dllu, CC BY-SA 4.0 via Wikimedia Commons

This 14-day trip visits Milan, Venice, Florence and Rome in sequence from north to south. Two days cover Milan landmarks and museums, then three days explore Venice including Murano and Burano. Four days in Florence focus on the historic center and Oltrarno before five days across Rome's ancient sites, Vatican and neighborhoods, with trains linking the cities.

14 daysFour citiesTrain travelMilan Venice Florence RomeBy travli· Checked by the travli team, September 2026

Day by day

Day 1

Milan: the Duomo and La Scala

  1. 9:00MilanSight
  2. 11:30MilanSight
  3. 14:00MilanSight
  4. 16:00MilanWalk
Day 2

Milan: the Last Supper and the Navigli

  1. 9:15MilanSight
  2. 11:00MilanSight
  3. 14:00MilanSight
  4. 18:00MilanWalk
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Day 3

To Venice

  1. 9:00Train to VeniceMilanTransfer
  2. 13:00VeniceWalk
  3. 14:00VeniceSight
  4. 16:00VeniceSight
Day 4

Venice: San Marco

  1. 9:00VeniceSight
  2. 10:30VeniceSight
  3. 13:30VeniceSight
  4. 15:00VeniceSight
Day 5

Murano and Burano

  1. 9:30Venetian LagoonDay trip
  2. 13:00Venetian LagoonSight
Day 6

Venice to Florence

  1. 10:00VeniceSight
  2. 13:30Train to FlorenceVeniceTransfer
  3. 17:00FlorenceSight
Day 7

Florence: the Duomo and the Uffizi

  1. 8:30FlorenceSight
  2. 10:30FlorenceSight
  3. 12:00FlorenceSight
  4. 15:00FlorenceSight
Day 8

Florence: David and the Medici

  1. 8:30FlorenceSight
  2. 11:00FlorenceSight
  3. 13:00FlorenceSight
  4. 15:30FlorenceSight
Day 9

Florence: the Oltrarno

  1. 9:30FlorenceWalk
  2. 10:30FlorenceSight
  3. 13:30FlorenceWalk
  4. 17:00FlorenceSight
  5. 18:30FlorenceSight
Day 10

To Rome

  1. 9:00Train to RomeFlorenceTransfer
  2. 13:00RomeSight
  3. 14:30RomeWalk
  4. 17:00RomeSight
Day 11

Rome: the ancient city

  1. 8:30RomeSight
  2. 11:00RomeSight
  3. 13:00RomeSight
  4. 16:00RomeSight
Day 12

Rome: the Vatican

  1. 8:30RomeSight
  2. 12:30RomeSight
  3. 15:30RomeSight
Day 13

Rome: Borghese and the Spanish Steps

  1. 9:00RomeSight
  2. 12:00RomeSight
  3. 15:00RomeSight
  4. 17:00RomeSight
Day 14

Rome: Trastevere

  1. 10:00RomeSight
  2. 12:00RomeSight
  3. 14:00RomeWalk
  4. 17:30RomeSight
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Questions about this trip

Is 14 days enough for Milan, Venice, Florence, and Rome?

Yes. Book trains between cities two to four weeks ahead and reserve major museum tickets online at the same time.

Do I need to book the Vatican Museums in advance?

Book timed-entry tickets at least two weeks ahead. Expect to pay 25 euros including the skip-the-line option.

Should I reserve train tickets from Milan to Venice before travel?

Reserve Frecciarossa seats online two weeks ahead. Prices start at 25 euros for the 2.5-hour trip when booked early.

Is it worth buying skip-the-line tickets for the Uffizi Gallery?

Yes. Book a timed ticket online at least ten days ahead to avoid long queues.

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