The Duomo di Milano cathedral in Milan under a soft orange and blue sky
Milan, Italy · 3 days itinerary

Milan: Weekend Escape

Photo by Ouael Ben Salah on Unsplash

This three-day trip covers Milan's Duomo, The Last Supper, Sforza Castle and major museums. The sequence starts in the central Duomo area, moves to timed sites like The Last Supper on day two, and ends with Brera and Sant'Ambrogio to group nearby locations efficiently. Walking routes connect sights within each day.

3 daysWalkableIncludes The Last SupperMilanBy travli· Checked by the travli team, September 2026

Day by day

Day 1

The Duomo and La Scala

  1. 9:00Milan CathedralDuomoSight
  2. 11:30DuomoSight
  3. 14:00DuomoSight
  4. 16:00BreraWalk
Day 2

The Last Supper and Sforza Castle

  1. 9:15The Last SupperSanta Maria delle GrazieSight
  2. 11:00Sforza CastleCastelloSight
  3. 13:30CastelloWalk
  4. 18:00NavigliWalk
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Day 3

Brera and Sant'Ambrogio

  1. 10:00BreraSight
  2. 13:00DuomoSight
  3. 16:00Sant'AmbrogioSight
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Milan questions

Is three days enough for Milan?

Three days covers the main sites with time for each. Book timed tickets in advance and use the metro between neighborhoods.

Do I need to book the Last Supper ahead?

Yes. Reserve online at least two weeks early through the official museum site. Slots fill quickly and cost about 15 euros per person.

How do I get from the Duomo to Castello Sforzesco?

Take the metro line 1 red from Duomo station to Cadorna or Cairoli. The ride takes under ten minutes and costs 2 euros with a single ticket.

When should I visit the Navigli canals?

Go in the late afternoon or evening after 17:00. The metro to Porta Genova or Romolo drops you within a short walk of the main canal stretch.

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